Polycystin-1 but not polycystin-2 deficiency causes upregulation of the mTOR pathway and can be synergistically targeted with rapamycin and metformin.

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Author : 
Mekahli, D ; Decuypere, JP ; Sammels, E ; Welkenhuyzen, K ; Schoeber, J ; Audrezet, MP & al
Newspaper edition : 
Pflugers Arch. - Année 2014 - Volume 466 - Page 1591-604 - PMID 24193408